Thermo Fisher, B7450, Brefeldin A (from <i>Penicillium brefeldianum</i>)

Name: Brefeldin A (from Penicillium brefeldianum )
Brand: Thermo Fisher
SKU: B7450

Quantity: 5 mg, Unit Size: Each

Catalog Number: B7450

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Category

Phosphorylation Reagents

Pack Size5 mg

TagsBioactive Small Molecules Protein Analysis Reagents

CollectionsThermo Fisher Protein Analysis Reagents for Western Blot, ELISA & Proteomics Thermo Fisher Clinical Analyzers & Instruments for Diagnostic Labs Thermo Fisher General Lab Supplies for Daily Workflows — Nalgene, Nunc, Samco & Matrix

Description

Quantity: 5 mg
Unit Size: Each
The fungal metabolite brefeldin A (BFA) has multiple targets in cells and has proven valuable for dissecting the cellular processes, including vesicle formation and kinesin distribution, involved in exporting newly synthesized proteins. We are pleased to offer the natural brefeldin A isolated from Penicillium brefeldianum. Exposing cells to BFA causes a distortion in intracellular protein traffic from the ER to the Golgi apparatus and the eventual loss of Golgi apparatus morphology; removal of BFA completely reverses these effects. BFA also alters the morphology of endosomes and lysosomes.Dissolve in high-quality anhydrous DMSO or ethanol to prepare a stock concentration up to 1 mM.

Specifications

General

Label Type	Unlabeled
Molecular Formula	C<sub>16</sub>H<sub>24</sub>O<sub>4</sub>
Molecular Weight (g/mol)	280.36
Quantity	5 mg
Recommended Storage	Store in freezer (-5°C to -30°C)
Shipping Condition	Room Temperature
Physical Form	Powder
Product Type	Sphingolipid
Unit Size	Each

Ordering

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