Description
Key facts
CAS number:1093757-42-6,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:316.2 Da,
Molecular formula:C14H15Cl2NO3,
PubChem:2933724,
Nature:Synthetic,
Solubility:Soluble in 1 eq. NaOH to 100 mMSoluble in DMSO to 100 mMSoluble in ethanol to 50 mM,
Biochemical name:2-[(3,5-dichlorophenyl)carbamoyl]cyclohexane-1-carboxylic Acid,
Biological description:Positive allosteric selective modulator at mGluR4 (EC50 values are 798 and 693 nM at human and rat mGluR4 receptors, respectively). It has advantages over PHCCC (ab120043) as it is more potent. Shows limited blood-brain barrier permeability. Active in behavioural models of Parkinson's disease following icv injection. Available in water-soluble form - please see VU0155041 sodium salt (ab120248).,
Canonical smiles:C1CCC(C(C1)C(=O)NC2=CC(=CC(=C2)Cl)Cl)C(=O)O,
InChi:InChI=1S/C14H15Cl2NO3/c15-8-5-9(16)7-10(6-8)17-13(18)11-3-1-2-4-12(11)14(19)20/h5-7,11-12H,1-4H2,(H,17,18)(H,19,20),
InChiKey:VSMUYYFJVFSVCA-UHFFFAOYSA-N,
IUPAC Name:2-[(3,5-dichlorophenyl)carbamoyl]cyclohexane-1-carboxylic acid
Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-Ambient, Appropriate long-term storage conditions-Ambient, Storage information-The product can be stored for up to 12 months
