Description
Key facts
CAS number:1335106-03-0,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:477.4 Da,
Molecular formula:C15H13F6N3O4S2,
PubChem:44241473,
Nature:Synthetic,
Solubility:Soluble in DMSO to 10 mM,
Biochemical name:N-[5-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]sulfamoyl]-4-methyl-1,3-thiazol-2-yl]acetamide,
Biological description:Potent, selective RORα and RORγt inverse agonist (Ki values are 172 and 111 nM for RORα and RORγ respectively). Suppresses IL-17 promoter driven transcriptional activity. Inhibits TRAP220 nuclear receptor box 2 peptide interaction (IC50 = 117 nM). Shows immunosuppressant effects in vivo.,
Canonical smiles:CC1=C(SC(=N1)NC(=O)C)S(=O)(=O)NC2=CC=C(C=C2)C(C(F)(F)F)(C(F)(F)F)O,
InChi:InChI=1S/C15H13F6N3O4S2/c1-7-11(29-12(22-7)23-8(2)25)30(27,28)24-10-5-3-9(4-6-10)13(26,14(16,17)18)15(19,20)21/h3-6,24,26H,1-2H3,(H,22,23,25),
InChiKey:OZBSSKGBKHOLGA-UHFFFAOYSA-N,
IUPAC Name:N-[5-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]sulfamoyl]-4-methyl-1,3-thiazol-2-yl]acetamide
Product details:
This product is manufactured by BioVision, an Abcam company and was previously called 1902 SR1001. 1902-25 is the same size as the 25 mg size of ab141462.
Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months
