Description
Key facts
CAS number:285983-48-4,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:527.7 Da,
Molecular formula:C31H37N5O3,
PubChem:156422,
Nature:Synthetic,
Solubility:Soluble in DMSO to 100 mMSoluble in ethanol to 50 mM,
Biochemical name:Doramapimod,
Biological description:Potent, selective, cell permeable p38 MAPK inhibitor (IC50 values of 38 nM, 65 nM, 200 nM and 520 nM for p38α/β/γ/δ respectively in vitro; Kd for p38α = 0.1 nM). Anti-inflammatory activity in vivo.,
Canonical smiles:CC1=CC=C(C=C1)N2C(=CC(=N2)C(C)(C)C)NC(=O)NC3=CC=C(C4=CC=CC=C43)OCCN5CCOCC5,
InChi:InChI=1S/C31H37N5O3/c1-22-9-11-23(12-10-22)36-29(21-28(34-36)31(2,3)4)33-30(37)32-26-13-14-27(25-8-6-5-7-24(25)26)39-20-17-35-15-18-38-19-16-35/h5-14,21H,15-20H2,1-4H3,(H2,32,33,37),
InChiKey:MVCOAUNKQVWQHZ-UHFFFAOYSA-N,
IUPAC Name:1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]urea
Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions
