Description
Key facts
CAS number:845538-12-7,
Purity:>98%,
Molecular weight:249.69 Da,
Molecular formula:C12H12ClN3O,
PubChem:11715766,
Nature:Synthetic,
Solubility:Soluble in DMSO to 10 mM,
Biochemical name:PHA-767491 hydrochloride,
Biological description:Potent Cdc7 and Cdk9 kinase inhibitor (IC50 values are 10 and 34 nM for Cdc7 in the presence of 1.5 μM ATP and Cdk9 respectively). Induces apoptosis in cancer cell lines. Shows synergistic antitumor effects in vivo with 5-fluorouracil (ab142387).,
Canonical smiles:C1CNC(=O)C2=C1NC(=C2)C3=CC=NC=C3.Cl,
InChi:InChI=1S/C12H11N3O.ClH/c16-12-9-7-11(8-1-4-13-5-2-8)15-10(9)3-6-14-12;/h1-2,4-5,7,15H,3,6H2,(H,14,16);1H,
IUPAC Name:2-pyridin-4-yl-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one;hydrochloride
Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months
