Description
Key facts
CAS number:1883545-60-5,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:411.3 Da,
Molecular formula:C18H24Cl2N6O,
PubChem:136664697,
Nature:Synthetic,
Solubility:Soluble in water to 100 mM,
Biochemical name:(R)-2-(4-((2-aminobutyl)amino)pyrimidin-2-yl)-4-(1-methyl-1H-pyrazol-4-yl)phenol dihydrochloride,
Biological description:Potent and selective protein kinase D inhibitor (IC50 values are 1, 2 and 2.5 nM at PKD1, PKD3 and PKD2, respectively). Reduces proliferation of pancreatic cancer cells. Orally active. Antitumor agent. Active in vivo and in vitro.Also available in simple stock solutions (ab146740) - add 1 ml of water to get an exact, ready-to-use concentration.,
Canonical smiles:CCC(CNC1=NC(=NC=C1)C2=C(C=CC(=C2)C3=CN(N=C3)C)O)N.Cl.Cl,
Isomeric smiles:CC[C@H](CNC1=NC(=NC=C1)C2=C(C=CC(=C2)C3=CN(N=C3)C)O)N.Cl.Cl,
InChi:InChI=1S/C18H22N6O.2ClH/c1-3-14(19)10-21-17-6-7-20-18(23-17)15-8-12(4-5-16(15)25)13-9-22-24(2)11-13;;/h4-9,11,14,25H,3,10,19H2,1-2H3,(H,20,21,23);2*1H/t14-;;/m1../s1,
InChiKey:CXYCRYGNFKDPRH-FMOMHUKBSA-N,
IUPAC Name:2-[4-[[(2R)-2-aminobutyl]amino]pyrimidin-2-yl]-4-(1-methylpyrazol-4-yl)phenol;dihydrochloride
Product details:
Sold under license from CRT.
Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months
