Description
Key facts
CAS number:389850-21-9,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:398.3 Da,
Molecular formula:C15H16BrN3O3S,
PubChem:11553038,
Nature:Synthetic,
Solubility:Soluble in DMSO to 100 mM,
Biochemical name:p-nitro-Pifithrin-alpha,
Biological description:Cell-permeable p53 inhibitor. Pifithrin-α (ab120478) analog and prodrug. Shows more potent antiapoptotic effects than pifithrin-α. Shows antiobesogenic and hepatoprotective effects in vivo.,
Canonical smiles:C1CCC2=C(C1)N(C(=N)S2)CC(=O)C3=CC=C(C=C3)[N+](=O)[O-].Br,
InChi:InChI=1S/C15H15N3O3S.BrH/c16-15-17(12-3-1-2-4-14(12)22-15)9-13(19)10-5-7-11(8-6-10)18(20)21;/h5-8,16H,1-4,9H2;1H,
InChiKey:NXPCMOGORSWOLH-UHFFFAOYSA-N,
IUPAC Name:2-(2-imino-4,5,6,7-tetrahydro-1,3-benzothiazol-3-yl)-1-(4-nitrophenyl)ethanone;hydrobromide
Product details:
It is important to note that this product has been reported to be unstable under a variety of conditions. In addition to being unstable to light and air after extended periods of time, this product is extremely unstable in polar solvents such as DMSO. Within 6 hours a DMSO solution had been found to be completely converted into the tricyclic material. We therefore recommend this material is only stored as the solid form at -20°C (or below), with the exclusion of light and air, and any solutions are made up fresh and used immediately.
Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store in the dark, Store under desiccating conditions, This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes
