Description
Key facts
CAS number:215543-92-3,
Purity:>98%,
Form:LiquidSee storage information,
Molecular weight:296.32 Da,
Molecular formula:C17H16N2O3,
PubChem:5289418,
Nature:Synthetic,
Biochemical name:3-[(3-(2-Carboxyethyl)-4-methylpyrrol-2-YL)methylene]-2-indolinone,
Biological description:Potent, selective VEGFR and FGFR inhibitor (IC50 values are 0.02 (VEGFR2), 0.03 (FGFR1), 0.51 (PDGFRβ) and >100 μM (EGFR)). Attenuates integrin β4-induced differentiation of neural stem cells. Shows antitumor effects in vivo.,
Canonical smiles:CC1=CNC(=C1CCC(=O)O)C=C2C3=CC=CC=C3NC2=O,
Isomeric smiles:CC1=CNC(=C1CCC(=O)O)/C=C\2/C3=CC=CC=C3NC2=O,
InChi:InChI=1S/C17H16N2O3/c1-10-9-18-15(11(10)6-7-16(20)21)8-13-12-4-2-3-5-14(12)19-17(13)22/h2-5,8-9,18H,6-7H2,1H3,(H,19,22)(H,20,21)/b13-8-,
InChiKey:JNDVEAXZWJIOKB-JYRVWZFOSA-N,
IUPAC Name:3-[4-methyl-2-[(Z)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid
Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store in the dark, Store under desiccating conditions, This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes
