Product detailsPatented technology Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on recombinant antibodies.
Alexa Fluor® is a registered trademark of Molecular Probes, Inc, a Thermo Fisher Scientific Company. The Alexa Fluor® dye included in this product is provided under an intellectual property license from Life Technologies Corporation. As this product contains the Alexa Fluor® dye, the purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). As this product contains the Alexa Fluor® dye the sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: in manufacturing; (ii) to provide a service, information, or data in return for payment (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are sold for use in research. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or
[email protected].
Supplementary informationThis supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
ABCD1 contributes to the maintenance of normal fatty acid levels within cells. It is not known as part of a larger protein complex but it cooperates closely with other peroxisomal enzymes to facilitate the beta-oxidation of VLCFAs. This action ensures the breakdown of toxic compounds and has a significant role in maintaining cellular homeostasis. The proper function of ABCD1 is essential for preventing the accumulation of VLCFAs which can affect cellular function and viability.
Pathways
ABCD1 is integral to the metabolic pathway of peroxisomal beta-oxidation. This pathway is important for the degradation of excess VLCFAs which are otherwise difficult to break down in mitochondria. ABCD1 works in concert with related proteins such as ABCD2 and ABCD3 playing differentiated yet sometimes overlapping roles in lipid transport and metabolism. This cooperation is important for maintaining normal cellular metabolism and preventing lipid accumulation.
