Description
Key facts
Sample types:Tissue sections
Product details:
PAS Stain Kit (Fungus, Periodic Acid Schiff Stain) ab245886 is intended for use in histological demonstration of fungal organisms in tissue sections. The PAS reaction is also useful in the demonstration of lymphocytes and mucopolysaccharides. The staining patterns of the lymphocytes are helpful in making therapeutic decisions in established cases of lymphocytic leukemia.Fungal Organisms: MagentaPAS Positive Material: MagentaOther Tissue Components: Green/Blue**Control Tissue:** Any fungal infected tissue. Kidney. Intestine. Liver.**Other products for staining tissue sections**Find more kits and reagents in the , or products for antigen retrieval, blocking, signal amplification, visualization, counterstaining, and mounting in the .
Properties and Storage Information:
Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-Multi, Storage information-Please refer to protocols
Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
The target often referred to by scientists as the fungal stain or PAS stain marks fungi and other polysaccharide-rich components. This target does not hold a specific molecular mass as it focuses on staining rather than a singular protein or molecule. It is expressed on the cell walls of fungi where complex carbohydrates are located. The PAS (Periodic Acid-Schiff) technique a popular method as kit fungus highlights these elements within specimens by staining them intensely.
Biological function summary
The PAS fungal stain method identifies fungi within biological tissues by reacting with glycol groups and converting them into aldehydes. It does not form part of a single protein complex but rather interacts with polysaccharides broadly distributed in various organisms. The technique is significant in studying the presence of fungal structures within samples especially in pathologic studies for disease diagnostics due to its specific interaction with carbohydrates.
Pathways
The PAS staining technique holds significance for identifying structures within the metabolic pathways that synthesize or degrade polysaccharides. This process aids in understanding how organisms like fungi utilize glycolysis and gluconeogenesis pathways. During these processes proteins such as glycosyltransferases are closely related as these proteins participate in the modification of polysaccharides which are important for the fungal stain's effectiveness.
The PAS stain method helps immensely in identifying fungal infections and certain types of neuromuscular disorders. For instance it is important for visualizing fungal elements in patient samples diagnosed with infections like candidiasis. Also it helps in detecting glycogen storage disorder-related conditions by identifying abnormal glycogen storage patterns. The association with the target involves proteins like glycogen phosphorylase related to glycogen breakdown which closely relate to how the PAS staining detects abnormal accumulations.
