Description
Key facts
CAS number:1189767-28-9,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:311.34 Da,
Molecular formula:C16H17N5O2,
PubChem:135908617,
Nature:Synthetic,
Solubility:Soluble in DMSO to >100 mM,
Biochemical name:Osoresnontrine,
Biological description:BI-409306 is a potent and selective PDE9A inhibitor (IC50 = 52 nM). Displays weak activity against other PDEs, such as PDE1A (IC50, 1.4 μM), PDE1C (IC50, 1.0 μM), PDE2A, PDE3A, PDE4B, PDE5A, PDE6AB, PDE7A, and PDE10A (IC50 > 10 μM). Potentially could be useful for the treatment of Alzheimer's disease and Schizophrenia.,
Canonical smiles:C1COCCC1N2C3=C(C=N2)C(=O)NC(=N3)CC4=CC=CC=N4,
InChi:InChI=1S/C16H17N5O2/c22-16-13-10-18-21(12-4-7-23-8-5-12)15(13)19-14(20-16)9-11-3-1-2-6-17-11/h1-3,6,10,12H,4-5,7-9H2,(H,19,20,22),
InChiKey:BZTIJCSHNVZMES-UHFFFAOYSA-N,
IUPAC Name:1-(oxan-4-yl)-6-(pyridin-2-ylmethyl)-5H-pyrazolo[3,4-d]pyrimidin-4-one
Product details:
This product is manufactured by BioVision, an Abcam company and was previously called B2377 BI-409306. B2377-25 is the same size as the 25 mg size of ab287027.
Properties and Storage Information:
Shipped at conditions-Blue Ice, Appropriate long-term storage conditions--20°C
