BD, 555691, Purified Mouse Anti-Human CD55 IA10

Name: Purified Mouse Anti-Human CD55 IA10
Brand: BD
SKU: 555691

0.1 mg

Catalog Number: 555691

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Category

Imaging Flow Cytometers

TagsReagents microscopy-imaging-reagents

CollectionsBD Microscopy & Imaging Reagents for IF/ICC/IHC BD Single-Cell Multiomics Reagents for the BD Rhapsody™ Platform BD Immunoassay Reagents: CBA, ELISA & ELISPOT for Cytokine Panels

Description

The IA10 monoclonal antibody specifically binds to CD55, which is also known as complement decay-accelerating factor (DAF). CD55 is a glycophosphatidylinositol (GPI)-anchored, single chain membrane glycoprotein of approximately 70 kDa that belongs to the regulators of complement activation (RCA) gene family which includes CD21, CD35, and CD46. CD55 is widely expressed on hematopoietic cells including platelets and erythrocytes, as well as on many non-hematopoietic cells, such as, endothelial cells and epithelial cells. CD55 is involved in protecting cells from damage by autologous activated complement complexes. CD55 prevents the amplification steps of the complement cascade by interfering with the assembly of the C3-convertases, C4b2a and C3bBb, and the C5-convertases, C4b2a3b and C3bBb3b.

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. Store undiluted at 4°C.
1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to www.bdbiosciences.com/us/s/resources for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.

Specifications

General

Brand	BD Pharmingen™
Alternative Name	DAF; CR; CROM; TC; Complement decay-accelerating factor
Reactivity	Human (QC Testing)
Isotype	Mouse IgG2a, κ
Immunogen	Purified Human Decay Accelerating Factor
Application	Flow cytometry (Routinely Tested), Immunohistochemistry-frozen (Reported)
Concentration	0.5 mg/ml
Workshop Number	V BP352, S031
RRID	AB_396042
Storage Buffer	Aqueous buffered solution containing ≤0.09% sodium azide.
Regulatory Status	RUO

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