Description
Description
Purcise™ Q Membrane is a novel anion exchange medium that modifies specific functional groups in a crosslinked polymer coating to achieve the separation and purification of negatively charged components.
Purcise™ Q membrane adsorber (chromatography) medium features sufficiently large pore channels that allow larger biomolecules to pass through, while enabling convective mass transfer on the channel surfaces, thus facilitating rapid binding of target molecules to ligand sites. Compared to traditional column chromatography media, membrane adsorber (chromatography) media offer higher process flow rates to shorten processing times and possess higher dynamic binding capacities for biomolecules (such as plasmid DNA, enveloped viruses, host cell proteins, etc.), thereby reducing process costs.
Features
High Binding Efficiency: Based on convective mass transfer, charged biomolecules are captured in a single pass through the membrane adsorber, without relying on retention time.
High Flow Rates: 10 MV/min within pressure limits by using membrane adsorbers increases productivity by 30-50 times compared to traditional packed-bed chromatography.
Linear Scalability and Flexibility: A full range of membrane adsorber, from process development to production scale.
Cost-effective: Compared to conventional column, it can significantly reduce overall costs at both the IND and commercial stages.
Easy to Use: Only a simple connection for immediate use.
Applications
Removal of contaminants such as host DNA, viruses, host cell proteins and endotoxins from biological fluids.
Capture of relatively large target molecules (e.g. recombinant proteins, plasmids, viral vectors and plasma fractions).
Purification of small molecules such as oligonucleotides and peptides.
Quality Standards
ISO 9001: 2015 Quality Management System
Manufactured for use in conformance with cGMP
Each product is integrity tested prior to release
COA/COQ provided with shipment
Validation documents are available upon request
