Cytiva, 17127303, SOURCE 30S, 1 L

Name: SOURCE 30S, 1 L
Brand: Cytiva
SKU: 17127303

Catalog Number: 17127303

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Category

Process-Scale Chromatography Resins

Pack Size1 L

TagsChromatography resins Ion exchange resins Chromatography products resin

CollectionsCytiva Chromatography Columns, Resins & Lab Glassware Cytiva Protein Analysis Equipment & Supplies Collection

Description

Source 30S is a polymeric, strong cation exchanger designed for intermediate purification and large-scale polishing.
Mono-sized 30 µm rigid beads gives low back pressure and high flow rates allowing for high productivity
Strong cation exchanger designed for high resolution polishing purification of proteins, peptides and oligonucleotides
High chemical stability allowing for wide range of working conditions with good resistance to cleaning conditions at high pH
SOURCE 30S is a synthetic high performance, preparative, chromatography resin, based on a 30 µm monosized, rigid polystyrene/divinyl benzene polymer matrix It is modified with sulphonate (S) strong cation exchange groups. SOURCE resins have excellent physical and chemical characteristics, allowing high flow rates and consistent performance at both laboratory and process scales.
SOURCE 30S is suitable for intermediate purification steps in industrial processes when large volumes of partially purified material need to be processed. A high degree of purification can be obtained with high productivity.
Through the combination of high quality assurance standards and a patented manufacturing process, particle structure is consistent both bead-to-bead and batch-to batch.
As member of the BioProcess resin range, SOURCE 30S meets industrial demands with security of supply and comprehensive technical and regulatory support.

Specifications

General

Chromatography technique	Ion Exchange Chromatography
BioProcess resin	Yes
Certificate of Analysis	Yes
Chemical stability	Stable in common ion exchange buffers
Ion Exchanger Type	Strong cation exchanger
Ligand	Sulphonate group
Ligand Coupling Method	long, hydrophilic spacer arms
Matrix	Polystyrene/divinylbenzene
Order Information	Process-scale quantities are available. Columns not suitable for use with ÄKTAprime plus system.
Particle size, d 50V	~30 µm
Pressure/Flow Specification	2000 cm/h, 1000 kPa, FineLine 100 column, bed height 10 cm
Storage	4 to 30°C, 20% Ethanol + 0.2 M Sodium Acetate
pH ligand fully charged	Entire pH range
pH stability, CIP	1–14
pH stability, operational	2–13

FAQs

Question: How does SOURCE 30S separate molecules?

Answer:It uses negatively charged sulfonate groups to bind positively charged molecules under suitable pH and conductivity.

Question: What is the package size?

Answer:1 L of bulk SOURCE 30S resin, suitable for packing a compatible chromatography column.

Question: Is SOURCE 30S the same as SOURCE 15S?

Answer:No. SOURCE 30S uses approximately 30 µm beads, whereas SOURCE 15S is a distinct smaller-particle grade.

Application Note

SOURCE 30S Strong Cation Exchange Chromatography Resin in the 1 L size supports development and operation of preparative ion-exchange methods before moving to larger bulk media packs. The medium uses rigid, approximately 30 µm monodisperse polystyrene/divinylbenzene particles functionalized with strong-acid sulfonate groups. Positively charged proteins and peptides can bind to this negatively charged stationary phase, with elution controlled through ionic strength and, where appropriate, pH. In development workflows, the 1 L format is useful for packing laboratory or pilot-scale columns and comparing resolution, capacity and flow behavior. Thoroughly equilibrate the packed column, control sample conductivity and collect fractions to identify separation performance. Small differences in buffer preparation and bed quality can alter peak shape, so document the packed-bed volume and system conditions. Cleaning, storage and regeneration steps should follow resin-compatible operating limits. The 1 L item contains the same SOURCE 30S media chemistry as the 5 L presentation but is not a smaller-particle SOURCE 15S grade.

Ordering

Notice

Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
All quotations are subject to final confirmation, including product availability, lead time, batch information, shipping cost, and applicable export or handling requirements.
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