Cytiva, 17547702, VIISelect, 200 mL

Name: VIISelect, 200 mL
Brand: Cytiva
SKU: 17547702

Catalog Number: 17547702

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Category

Recombinant Growth Factors

Pack Size200 mL

TagsChromatography resins Chromatography products Affinity resins - specific groups resin

CollectionsCytiva Chromatography Columns, Resins & Lab Glassware Cytiva Protein Analysis Equipment & Supplies Collection

Description

VIISelect is an affinity chromatography resin designed for the purification of Factor VII/VIIa
Affinity chromatography resin with high selectivity for efficient industrial purification of Factor VII
Rigid agarose base matrix allows high flow rates and processing of large sample volumes for increased throughput
Non-mammalian derived product reduces regulatory concerns
Efficient processes for the purification of recombinant blood coagulation factors are needed in the development of treatments for hemophilia patients. VIISelect is an affinity resin designed for the purification of Factor VII/VIIa, a blood factor used for treatment of hemophilia patients who have developed inhibitors against replacement coagulation factors. It can be used, under mild elution conditions, for purifying Factor VII from plasma as well as from recombinant sources.

Specifications

General

Chromatography technique	Group specific affinity
BioProcess resin	No
Ligand	Recombinant protein (M r 14 080) produced in Saccharomyces cerevisiae
Ligand density	Approx. 5.7 mg/ml of medium
Matrix	Highly cross-linked, high-flow agarose
Particle size, d 50V	~75 µm
Pressure/Flow Specification	At least 600 cm/h in a 1 m column with 20 cm bed height at 20°C using process buffers with the same viscosity as water at < 3bar (0.3 Mpa)
pH stability, CIP	2–12
pH stability, operational	3–10

Ordering

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