Answer:It is used to normalize detector response in compatible Biacore SPR systems during instrument maintenance.
Answer:No. It is a 70% (w/w) glycerol normalization solution, not a routine running buffer.
Answer:The product is supplied as a 90 mL liquid bottle.
BIAnormalizing Solution is a 70% (w/w) glycerol reference solution used to normalize detector response in compatible Biacore surface plasmon resonance systems. Normalization helps align the instrument's optical response with a defined refractive-index reference, supporting consistent sensorgram evaluation and routine maintenance. The reagent is supplied as a ready-to-use 90 mL liquid rather than a running buffer, ligand-coupling agent or regeneration solution. Before the procedure, allow the instrument and solutions to reach the conditions required by the relevant maintenance method. Apply normalization through the system's dedicated software routine and confirm completion of the prescribed performance checks. Normalization is distinct from cleaning the flow path or testing a specific biomolecular interaction. Store at 2–8°C, keep the container closed when not in use and avoid introducing particulate matter or cross-contamination.
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