Cytiva, 29317029, ReadyToProcess Capto adhere 25 L (359/250)

About Capto adhere resins Capto adhere is a multimodal anion exchange chromatography resin for intermediate purification and polishing of monoclonal antibodies after the Protein A capture step, giving the possibility to design a two-step chromatographic downstream process. Enables a two-step chromatographic process The resin is composed of a rigid, high-flow agarose matrix and a novel multimodal ligand. The strong multimodal ligand gives a different selectivity compared with traditional ion exchangers. Capto adhere can remove key contaminants such as DNA, host cell proteins (HCP), leached protein A, dimers and larger aggregates, and viruses in a single step. Together with a Protein A capture resin, like MabSelect PrismA, Capto adhere allows the design of a two-step chromatographic process for mAbs. For optimized performance of Capto adhere, screening and optimization of loading conditions is recommended, preferably using modern high-throughput process development tools, such as PreDictor 96-well filter plates. Key benefits of ReadyToProcess columns include: Robust column design and verified packing methods enable consistent column performance. No need for column preparation, packing, and validation procedures. Manage timelines and minimize delays with a single supplier for resins and columns. Fulfills industrial demands for security of supply, robust performance, and regulatory support.