Description
Compare ÄKTA ready™ systems System ÄKTA ready™ 450 ÄKTA ready™ ÄKTA ready™ variable UV and extended ÄKTA ready™ XL Flow rate and tubing size 1/8 inch: 5-450 ml/min 1/4 inch: 3-175 L/h (Low Flow Kit) 3/8 inch: 7.5-510 L/h (High Flow Kit) 3/4 inch: 45-1900 L/h 1 inch: 90-3500 L/h Target applications Small-scale GMP manufacturing of viral vectors, nucleic acids, ADC’s and other sensitive biologics Clinical scale purification of monoclonal antibodies (mAbs), antibody fragments, biosimilars and other similar protein biologics Clinical scale purification with additional capabilities for flexibility in multi-product facilities Large-scale GMP manufacturing of biologics UV Simultaneous, three-wavelength variable UV sensor 280 nm Simultaneous, three-wavelength variable UV sensor Connectors TriClamp™ and AseptiQuik® TriClamp™, ReadyMate™ and AseptiQuik® TriClamp™, ReadyMate™ and AseptiQuik® TriClamp™ and AseptiQuik® Human-machine interface (HMI) External HMI External HMI External HMI (variable UV) Integrated HMI (extended) Integrated HMI Mixer control N/A N/A Xcellerex™ XDUO mixer connected through PROFIBUS (extended) Xcellerex™ XDUO mixer connected through PROFIBUS Explore ÄKTA ready extended system in 3D Purification formats Columns ReadytoProcess™ columns from 8 cm to 600 cm inner diameter Standard bed heights 15, 20 and 25 cm (custom bed heights from 10 to 24 cm) AxiChrom™ columns 50 to 1200 mm inner diameter Membranes Mustang™ membranes in Acrodisc™ filters or Kleenpak™ capsules 0.86 to 5000 ml ÄKTA ready™ 450 system data file | ÄKTA ready™ system data file | ÄKTA ready™ XL system data file Flow kits The flow kits include a single-use pump head and tubing, with integrated sensors for pressure, conductivity, temperature, flow, UV, and pH (depending on the flow kit; see ordering information for details). Flow kits for ÄKTA ready 450 system are designed with a valve block to snap into place for each installation. For the other ÄKTA ready systems, order the required size flow kit for isocratic elution or add the gradient section for gradient elution. Visit product page for the flow kits System software UNICORN™ software provides intuitive and flexible method creation, system control, and process evaluation to simplify your purification workflows. Connecting flow kits is quick and easy and can be confirmed by an installation test within the software. For users who require chromatography equipment to be used on their facility’s plant-wide automation platform, ÄKTA ready™ systems can be customized with a distributed control system or can connect to automation options via Open Platform Communications-Unified Architecture (OPC-UA). Visit the UNICORN™ software product page . Application data Article: Connected polishing and concentration under one automation method