Description
The iCELLis™ bioreactor systems are available in three formats: The iCELLis™ Nano system for process development and small-scale production (0.5 to 4 m ^2 ) The iCELLis™ 50 system for pilot-scale process development and medium-scale clinical manufacturing (6 to 50 m ^2 ) The iCELLis™ 500+ system for industrial scale manufacturing (66 to 500 m ^2 ) Detailed product information is available on the product datasheet. User software and automation The iCELLis™ bioreactor family is built with our innovative mPath™ Link user interface, which has become an integral part of the Cytiva automation platform. It focuses on supervisory control and data acquisition with recipe management, aiming to provide an automation ecosystem for bioprocess scientists and engineers. The mPath™ Link software was designed for use in both GMP-regulated and process development environments, meeting all the requirements of an industrial manufacturing environment, including compliance with 21 CFR Part 11 or EudraLex Annex 11. The mPath™ Link software includes tools such as real-time data trending, customizable control loops, on screen operational instructions, recipe management, and reporting. These features make it a powerful tool to help you quickly understand and scale up your process. For more detailed information on the mPath™ control towers or software, please visit http://www.cytiva.com/mpathlink . High productivity, reduced footprint The fixed-bed design of the iCELLis™ bioreactor system makes it well-suited for industrialization of adherent cell processes for both gene therapy and vaccines, providing a large cell growth surface area while keeping the footprint very small. The iCELLis™ bioreactor system accommodates up to 500 ^m2 of growth area, which, when compared with available surfaces of multitray systems and roller bottles, corresponds to a huge reduction in footprint. The iCELLis™ 500+ 500 m ^2 system is equivalent to 794 cell stacks with 10 trays and 5882 roller bottles at 850 cm ^2 each. In addition to footprint reduction, the iCELLis™ bioreactor enables high productivity due to the ability to precisely control process parameters such as pH and dissolved oxygen (DO).
