| EC Index Number | 231-449-2 |
|---|---|
| E Number | E339 |
| UNSPSC Code | 12352302 |
| MDL number | MFCD00149209 |
| InChI | 1S/Na.H3O4P.2H2O/c;1-5(2,3)4;;/h;(H3,1,2,3,4);2*1H2/q+1;;;/p-1 |
| InChI key | VBJGJHBYWREJQD-UHFFFAOYSA-M |
| agency | BP |
| product line | EMPROVE® ESSENTIAL |
| form | solid |
| pH | 4.5 (25 °C, 12 g/L in H2O) |
| mp | 60 °C |
| solubility | 850 g/L |
| density | 1.915 g/cm3 at 20 °C |
| application(s) | liquid formulationophthalmicspharmaceuticalsemi-solid formulationsolid formulation |
| storage temp. | 2-30°C |
| Quality Level | 500 |
| SMILES string | O.O.[Na+].OP(O)([O-])=O |
Answer:It is a component of phosphate buffer systems used in downstream chromatography and liquid formulation.
Answer:The formula is NaH2PO4·2H2O, and its molecular weight is 156.01 g/mol.
Answer:The grade lists Ph. Eur., BP, ChP, JPE, USP, and E339 designations.
Sodium dihydrogen phosphate dihydrate is a sodium phosphate salt used to prepare phosphate buffering systems for bioprocess chromatography and liquid pharmaceutical formulations. The Emprove Essential grade supports raw-material selection where a defined quality profile and documented regulatory attributes are important. The chemical formula is NaH2PO4·2H2O, with a molecular weight of 156.01 g/mol and CAS number 13472-35-0. In downstream processing, the salt is a source of monobasic phosphate for setting buffer composition alongside the appropriate conjugate phosphate component. The final pH, buffer capacity, and ionic strength depend on the complete formulation rather than on the salt alone. Pharmaceutical development teams can use this material in phosphate-based liquid formulations where relevant compendial specifications and material documentation are required. The grade is associated with Ph. Eur., BP, ChP, JPE, and USP designations and the E339 designation. The Emprove documentation package is useful for material qualification and change-control workflows; formulation suitability remains dependent on the target process and its specifications.
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