Merck, 1200930500, Eshmuno® CP-FT Resin
Size:500 mL, Eshmuno® CP-FT
Catalog Number: 1200930500
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Pack Size500 mL
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| UNSPSC Code | 41115711 |
|---|---|
| Quality Level | 400 |
| ligand | (Sulfoisobutyl) |
| sterility | sterile (Caustic Stable) |
| product line | Eshmuno® |
| form | resin |
| specific analyte(s) | MAbs |
| parameter | 400 cm/hr flow rate |
| matrix active group | polymer, polyvinyl ether |
| mean particle size | 50 μm |
| capacity | 70 mg binding capacity (lysozyme/ml of resin) |
| transition temp | flash point 35 °C |
| separation technique | strong cation exchange |
| storage temp. | 2-30°C |
Answer:It is a strong cation-exchange resin designed for flow-through frontal chromatography.
Answer:It is designed to remove monoclonal-antibody aggregates while allowing the desired monomer to pass through.
Answer:This configuration contains 500 mL of resin.
Eshmuno® CP-FT Resin is used as a strong cation-exchange polishing resin for flow-through removal of monoclonal-antibody aggregates. The sulfoisobutyl ligand is grafted onto a rigid hydrophilic polyvinyl-ether polymer matrix with a mean particle size of about 50 µm. The resin is designed for frontal chromatography, allowing the monomeric antibody to pass through while aggregate impurities are retained under suitable loading conditions. The rigid bead structure supports linear flow rates up to about 400 cm/h and the resin tolerates pressures up to 8 bar, helping process developers intensify polishing operations and reduce column size and buffer volume. This 500 mL configuration is useful for process development, scale-up and manufacturing studies that require a high-throughput CEX step with strong chemical stability and compatibility with alkaline cleaning conditions.
Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
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