Merck, 14366C-1000ML, EX-CELL® Advanced CHO Fed-batch Medium

Name: EX-CELL® Advanced CHO Fed-batch Medium
Brand: Merck
SKU: 14366C-1000ML

Size:1000 mL, liquid

Catalog Number: 14366C-1000ML

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Category

Chemically Defined Media

Pack Size1000 mL

TagsCell Culture & Analysis Cell Culture Media & Buffers Bioprocessing Cell Culture Media

CollectionsMerck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
EX-CELL® AdvancedCHO Fed-batch Medium is chemically-defined and contains no animal derived components. This newest platform from SAFC has been specifically developed to support growth and productivity across a diverse set of Chinese Hamster Ovary (CHO) cells in fed-batch cultures while still allowing for flexibility in the adjustment of protein quality attributes. This contemporary fed-batch platform was developed using a strategy of Multivariate Analysis to establish correlations in which the formulation components influence critical process and product attributes such as titer, fold expansion, receptor expression, and glycosylation. This platform contains no hypoxanthine and thymidine, L-glutamine, phenol red or 2-mercaptoethanol (2-ME). This medium is intended to be a part of a fed-batch platform, and used with EX-CELL® Advanced CHO Feed 1 (24367C - with glucose or 24368C - without glucose).
Legal Information
EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Donot freeze. Protect from light. Several components of the medium arelight labile and should not be exposed to light for lengthy periods of time.

Specifications

General

NACRES	NA.75
UNSPSC Code	41161501
sterility	sterile-filtered
product line	EX-CELL®
form	liquid
Quality Level	500
feature	subscription eligible
technique(s)	cell culture \| mammalian: suitable (suspension)
components	L-glutamine: no
shipped in	ambient
storage temp.	2-8°C

FAQs

Question: Is this medium chemically defined?

Answer:Yes. It is chemically defined and contains no animal-derived components.

Question: Does it contain L-glutamine?

Answer:No. L-glutamine is not included in the formulation.

Question: How should the medium be stored?

Answer:Store the liquid medium at 2–8 °C.

Application Note

EX-CELL® Advanced CHO Fed-batch Medium is a chemically defined liquid medium for suspension culture of CHO cells in fed-batch bioprocess workflows. The formulation contains no animal-derived components and is sterile filtered. It is designed to be paired with EX-CELL Advanced CHO Feed 1 as part of an integrated fed-batch platform. L-glutamine, hypoxanthine and thymidine, phenol red, and 2-mercaptoethanol are not included, allowing these components to be managed separately when required by the process. The medium is suitable for mammalian suspension culture and is endotoxin tested. This SKU contains 1 L of liquid medium and is stored at 2–8 °C. It can support process-development studies and production-oriented CHO workflows where a defined basal medium and controlled feeding strategy are preferred.

Ordering

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