Merck, 53591-U, Ascentis® Express F5, 2.7 μm HPLC Column

Name: Ascentis® Express F5, 2.7 μm HPLC Column
Brand: Merck
SKU: 53591-U

Size:1 ea, Core-shell (SPP) Fused Core PFP HPLC column, 2.7 μm particle size, L × I.D. 15 cm × 4.6 mm

Catalog Number: 53591-U

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Category

Chiral HPLC Columns

Pack Size1 ea

TagsHPLC Columns Analytical Chemistry Analytical Chromatography

CollectionsMerck Analytical Chromatography Products & Lab Supplies Merck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
The pentafluorophenylpropyl stationary phase of Ascentis Express F5 provides a stable reversed phase packing with electron-deficient phenyl rings due to the presence of electronegative fluorines.In addition to forming pi-pi and mildly steric interactions, F5 phases also retain compounds by polar interactions. Ascentis Express F5 can be used for basic, acidic, or neutral compounds with alternate selectivity from C18.
Application

Liquid chromatographic determination of lumacaftor in the presence of ivacaftor and identification of five novel degradation products using high-performance liquid chromatography ion trap time-of-flight mass spectrometry.: This study demonstrates the use of high-performance liquid chromatography (HPLC) with ion trap time-of-flight mass spectrometry for the determination of lumacaftor in the presence of ivacaftor. The research identifies five novel degradation products, showcasing the advanced analytical capabilities of the Ascentis® Express F5, 2.7 µm HPLC Column for complex mixtures and degradation studies (Özcan et al., 2023).

Stability-indicating LC-MS/MS and LC-DAD methods for robust determination of tasimelteon and high resolution mass spectrometric identification of a novel degradation product.: This paper details the development of stability-indicating methods using LC-MS/MS and LC-DAD for the determination of tasimelteon. It highlights the robustness and sensitivity of these methods in identifying novel degradation products, with the Ascentis® Express F5 column playing a crucial role in separation efficiency and stability analysis (Özcan et al., 2020).

Recent trends in ultra-fast HPLC: new generation superficially porous silica columns.: This review article discusses recent advancements in ultra-fast HPLC, focusing on new generation superficially porous silica columns, including the Ascentis® Express F5, 2.7 µm HPLC Column. It provides insights into the enhanced performance, speed, and efficiency of these columns in high-throughput analytical applications (Ali et al., 2012).

Legal Information
Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany

Specifications

General

UNSPSC Code	41115700
eCl@ss	32110501
Web Name Suffix Override	L × I.D. 15 cm × 4.6 mm, HPLC Column
Web Name Override	Ascentis® Express 90 Å F5 (2.7 μm) HPLC Columns
NACRES	SB.52
material	stainless steel column
agency	suitable for USP L43
product line	Ascentis®
feature	endcapped
manufacturer/tradename	Ascentis®
packaging	1 ea of
parameter	60 °C temp. range
technique(s)	HPLC: suitable
L × I.D.	15 cm × 4.6 mm
surface area	135 m2/g
impurities	<5 ppm metals
matrix	Fused-Core particle platform
matrix active group	PFP (pentafluorophenyl) phase
particle size	2.7 μm
pore size	90 Å pore size
operating pH	2-8
application(s)	food and beverages
separation technique	reversed phase
Quality Level	100

Ordering

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