General descriptionLithium dimethylaminoborohydride is a reagent exhibiting dual properties like a metal hydride and nitrogen nucleophile. It is generally considered as an alternative to lithium aluminum hydride (LAH) for the reduction of carbonyl compounds, amides, and lactams.
ApplicationCapable of reducing a variety of fuctional groups.
LABs can transfer the amine moiety, as in the case of the reaction with halopyridines and primary alkyl methanesulfonates.
Lithium Aminoborohydride (LAB) Reagents
Reactant for:
- B-H oxidative addition reactions
- Reduction and amination reactions
- Reduction of N-alkyl lactams
- Synthesis of tertiary amine-boranes