Description
General description
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[poly(ethylene glycol)2000-N′-carboxyfluorescein] (18:0 PEG2000 PE CF) lipid comprises hydrophilic polyethylene glycol (PEG) polymer in its head groups. DSPE-PEG(2000) micelles exist as spheroid in aqueous solution.
Application
18:0 PEG2000 PE CF may be used:
in in vitro release assays from nanoemulsion (NE)
for the labeling PEGylated LPD (liposome-polycation-DNA) for size exclusion chromatography studies
as a fluorescent probe to monitor shape transformation in giant vesicles
Biochem/physiol Actions
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[poly(ethylene glycol)2000-N′-carboxyfluorescein] (18:0 PEG2000 PE CF) micelles aid in nanoparticles based drug delivery. It has potential to solubilize hydrophobic drugs and aid in the controlled release of drugs. 18:0 PEG2000 PE CF also called the DSPE−PEG2000, prevents the uptake of drugs by mononuclear phagocyte system and is a potential drug carrier for cancer therapy.
Packaging
5 mL Clear Glass Sealed Ampule (810120P-1mg)
5 mL Clear Glass Sealed Ampule (810120P-500ug)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC