Merck, A6284-5ML, Human IgG−Agarose

Name: Human IgG−Agarose
Brand: Merck
SKU: A6284-5ML

Size:5 mL, IgG Agarose, suspension

Catalog Number: A6284-5ML

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Category

Substrate Solutions

Pack Size5 mL

CollectionsMerck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
Human IgGs are glycoprotein antibodies that contain two equivalent light chains and a pair of identical heavy chains. IgGs have four distinct isoforms, ranging from IgG1 to IgG4. These antibodies regulate immunological responses to allergy and pathogenic infections. IgGs have also been implicated in complement fixation and autoimmune disorders.
Application
IgG-Agarose is an immuno-adsorbent that can be used to affinity purify antibodies, remove species-specific cross-reacting antibodies or remove contaminating antibodies from an antiserum preparation. Typically, cross-reacting antibodies may be removed from an antiserum preparation using an equal volume of IgG-Agarose (resin volume). However, the resin to antiserum ratio will vary with individual applications.
Tandem affnitiy purification pulldown was performed in yeast cultures using agarose-linked human IgG. Supernatants were mixed with 30μl of agarose beads overnight.
Physical form
Suspension in 0.5 M NaCl containing preservative.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Specifications

General

UNSPSC Code	12352203
NACRES	NA.46
MDL number	MFCD00147242
conjugate	agarose conjugate
form	suspension
extent of labeling	≥5 mg per mL
matrix	Cross-linked 4% beaded agarose
matrix activation	cyanogen bromide
matrix spacer	1 atom
storage temp.	2-8°C
Quality Level	200

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Merck, A6284-5ML, Human IgG−Agarose

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