Merck, A9135-100MG, Ethyl arachidonate

Name: Ethyl arachidonate
Brand: Merck
SKU: A9135-100MG

Size:100 mg, 5, 8, 11, 14-Eicosatetraenoic acid ethyl ester, Arachidonic acid ethyl ester, ≥98.5% (GC), liquid

Available Catalog Numbers

A9135-100MG A9135-1G

Catalog Number: A9135-100MG

Pricing

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Category

Lipid Supplements

Pack Size100 mg

TagsChemistry & Biochemicals Biochemicals Lipids

CollectionsMerck Biochemicals Collection: Trusted Lab Reagents & Buffers Merck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

Biochem/physiol Actions
Arachidonic acid (AA) is an unsaturated omega-6 fatty acid constituent of the phospholipids of cell membranes. Phospholipase A2 releases AA from the membrane phospholipids in response to inflammation. AA is subsequently metabolized to prostaglandins and thromboxanes by at least two cyclooxygenase (COX) isoforms, to leukotrienes and lipoxins by lipoxygenases, and to epoxyeicosatrienoic acids via p450-catalyzed metabolism. AA and its metabolites play important roles in a variety of biological processes, including signal transduction, contraction, chemotaxis, and cell proliferation, differentiation and apoptosis. AA has been demonstrated to bind to the α subunit of G protein and inhibit the activity of Ras GTPase-activating proteins (GAPs). Cellular uptake of AA is energy dependent and involves protein-facilitated transport across the plasma membrane.
Packaging
Sealed ampule.

Specifications

General

NACRES	NA.25
PubChem Substance ID	24891398
UNSPSC Code	12352211
MDL number	MFCD00038340
InChI	1S/C22H36O2/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24-4-2/h8-9,11-12,14-15,17-18H,3-7,10,13,16,19-21H2,1-2H3/b9-8-,12-11-,15-14-,18-17-
SMILES string	CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OCC
InChI key	SNXPWYFWAZVIAU-GKFVBPDJSA-N
biological source	fungus
assay	≥98.5% (GC)
form	liquid
functional group	ester
lipid type	omega FAs
shipped in	ambient
storage temp.	−20°C
Quality Level	100

Ordering

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