Merck, C1484-25MG, 7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin

Name: 7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin
Brand: Merck
SKU: C1484-25MG

Size:25 mg, 1H-Pyrrole-2, 5-dione, 1-(4-(7-(diethylamino)-4-methyl-2-oxo-2H-1-benzopyran-3-yl)phenyl)-, CPM, ≥95% (HPLC), solid

Catalog Number: C1484-25MG

Pricing

Send an RFQ.

View RFQ List

Category

Special Stains

Pack Size25 mg

TagsClinical & Diagnostics Tissue Diagnostics Hematology Stains

CollectionsMerck Tissue Diagnostics – Universal Reagents for Histology & IHC Merck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin (CPM), is a highly fluorescent, sulfhydryl (-SH) group containing coumarin derivative. It has excitation an emission wavelengths of 355 and 460 nm, respectively.
Application
7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin has been used:
as a nontoxic substitute for conjugation with antibody(93)
to aid fluorescent detection of Coenzyme A (CoA-SH) in human N-myristoyltransferases assay (94)
in thermostability shift assay of recombinant protein(95)

Biochem/physiol Actions
Used to monitor release of thiols, quantitate thiol in microplate reactions, and to distinguish proliferating cancer cells by nucleolar protein staining.

Specifications

General

UNSPSC Code	12171500
PubChem Substance ID	24892413
NACRES	NA.47
Web Name Suffix Override	≥95% purity (HPLC), solid
MDL number	MFCD00077334
SMILES string	CCN(CC)c1ccc2C(C)=C(C(=O)Oc2c1)c3ccc(cc3)N4C(=O)C=CC4=O
InChI	1S/C24H22N2O4/c1-4-25(5-2)18-10-11-19-15(3)23(24(29)30-20(19)14-18)16-6-8-17(9-7-16)26-21(27)12-13-22(26)28/h6-14H,4-5H2,1-3H3
InChI key	YGIABALXNBVHBX-UHFFFAOYSA-N
assay	≥95% (HPLC)
form	solid
technique(s)	titration: suitable
color	yellow
solubility	DMSO: soluble
application(s)	diagnostic assay manufacturinghematologyhistology
storage temp.	−20°C
Quality Level	100

Ordering

Notice

Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
All quotations are subject to final confirmation, including product availability, lead time, batch information, shipping cost, and applicable export or handling requirements.
For quotation requests, please send an RFQ from website or contact:

[email protected]

Please send inquiries directly to us in the “To” field. Emails sent via BCC, mass mailing, or with unrelated recipients may be automatically filtered and will not be processed.