Merck, SAB3700674-1MG, Anti-Rat IgM (μ-chain specific)-Biotin antibody produced in goat

General description
An immunoglobulin has two heavy chain and two light chain connected by disulfide bond. It mainly helps in immune defense. It is a glycoprotein. IgG is a major class of immunoglobulin. Immunoglobulin M (IgM) belongs to the immunoglobulin family. It exists as a pentamer in the serum and has a high molecular weight. Monomeric IgM has a molecular weight of 190 kDa. Rat has five immunoglobulin classes- IgM, IgG, IgA, IgD and IgGE. IgM is present on the surface of the B lymphocytes in its monomeric form. This IgM serve as an antigen receptor to activate antibody response.
Antibody format: IgG
Immunogen
Rat IgM mu heavy chain
Biochem/physiol Actions
This product was prepared from monospecific antiserum by immunoaffinity chromatography using Rat IgM coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against Anti-Biotin, Anti-Goat Serum, Rat IgM and Rat Serum. No reaction was observed against Rat IgA or Rat IgG.
Physical form
Supplied in 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free
Preparation Note
Reconstitute with 1.0 mL deionized water (or equivalent).
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.