Merck, SBR00057-50MG, Retapamulin

Name: Retapamulin
Brand: Merck
SKU: SBR00057-50MG

Size:50 mg, ≥98% (HPLC)

Catalog Number: SBR00057-50MG

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Category

Mixed-Mode Resins

Pack Size50 mg

CollectionsMerck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
Retapamulin (RET) is a semi-synthetic antibiotic ointment, and pleuromutilin derivative compound. The primary structural difference between pleuromutilin and retapamulin is in the C-14 side chain.
Biochem/physiol Actions
Retapamulin is a potent antibacterial agent against Gram-positive bacteria, especially against Staphylococcus aureus and S. pyogenes. It displays synergistic effects against Enterococcus faecalis in combination with streptogramin (MLS). RET initiates ribosomal arrests at the start codon and enables genes to use alternative translational sites in E. coli.

Specifications

General

UNSPSC Code	51284706
NACRES	NA.76
MDL number	MFCD11045316
SMILES string	S(C4C[C@@H]5N([C@@H](CC5)C4)C)CC(=O)O[C@H]1[C@]2([C@H]3[C@@]([C@H]([C@@H]([C@](C1)(C)C=C)O)C)(CC[C@H]2C)CCC3=O)C
InChI	1S/C30H47NO4S/c1-7-28(4)16-24(35-25(33)17-36-22-14-20-8-9-21(15-22)31(20)6)29(5)18(2)10-12-30(19(3)27(28)34)13-11-23(32)26(29)30/h7,18-22,24,26-27,34H,1,8-17H2,2-6H3/t18-,19+,20-,21+,22?,24-,26+,27+,28-,29+,30+/m1/s1
InChI key	STZYTFJPGGDRJD-FJJJPKKESA-N
assay	≥98% (HPLC)
form	powder
antibiotic activity spectrum	Gram-positive bacteria
mode of action	protein synthesis \| interferes
storage temp.	−20°C
Quality Level	100

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