Merck, SCP0158-5MG, Granzyme B Substrate

Name: Granzyme B Substrate
Brand: Merck
SKU: SCP0158-5MG

Size:5 mg

Catalog Number: SCP0158-5MG

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Category

ELISA Substrates

Pack Size5 mg

CollectionsMerck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

Application
Granzyme B Substrate (Ac-IEPD-AMC) is a fluorogenic substrate for the detection and assay of caspase 8 and granzyme B which is involved in the rapid induction of target cell apoptosis by CTL in cell-mediated immune response.
Biochem/physiol Actions
Granzymes belongs to serine proteinase family enzymes and it localizes along with perforin in granules. It is predominant in cytotoxic T cells. Granzyme B induces caspases dependent and independent cell death. It possesses specific cleavage action at aspartate residue in the substrate.

Specifications

General

UNSPSC Code	12352204
Web Name Suffix Override	≥95% (HPLC), lyophilized
NACRES	NA.32
assay	≥95% (HPLC)
form	lyophilized
composition	Peptide Content, ≥85%
storage condition	protect from light
storage temp.	−20°C

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