Merck, SML3102-10MG, Ceftaroline fosamil acetate hydrate

Name: Ceftaroline fosamil acetate hydrate
Brand: Merck
SKU: SML3102-10MG

Size:10 mg, 4-(2-((6R, 7R)-2-Carboxy-7-((Z)-2-(ethoxyimino)-2-(5-(phosphonoamino)-1, 2, 4-thiadiazol-3-yl)acetamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-ylthio)thiazol-4-yl)-1-methylpyridinium acetate, hydrate, Ceftaroline fosamil acetate hydrate, PPI 0903 hydrate, PPI-0903 hydrate, PPI0903 hydrate, TAK 599 hydrate, TAK-599 hydrate, TAK599 hydrate, ≥98% (HPLC)

Available Catalog Numbers

SML3102-10MG SML3102-50MG

Catalog Number: SML3102-10MG

Pricing

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Category

Bacterial Expression Systems

Pack Size10 mg

CollectionsMerck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

Biochem/physiol Actions
Ceftaroline fosamil (PPI-0903, TAK-599) is a N-phosphono type prodrug of ceftaroline (cephalosporin 2a, PPI-0903M, T-91825), a fifth-generation penicillin-binding protein (PBP)-targeting cephalosporin class beta-lactam (β-lactam) antibiotic with broad-spectrum activity against gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and extensively-resistant strains, such as vancomycin-intermediate S. aureus (VISA), heteroresistant VISA (hVISA), and vancomycin-resistant S. aureus (VRSA).
N-phosphono type prodrug of ceftaroline, a fifth-generation PBP-targeting cephalosporin antibiotic against gram-positive bacteria, including MRSA.

Specifications

General

UNSPSC Code	12352200
NACRES	NA.77
Web Name Suffix Override	≥98% (HPLC), bacterial cell wall synthesis inhibitor, powder
MDL number	MFCD29920090
InChI	1S/C22H21N8O8PS4.C2H4O2/c1-3-38-26-13(16-25-21(43-28-16)27-39(35,36)37)17(31)24-14-18(32)30-15(20(33)34)12(9-40-19(14)30)42-22-23-11(8-41-22)10-4-6-29(2)7-5-10;1-2(3)4/h4-8,14,19H,3,9H2,1-2H3,(H4-,24,25,27,28,31,33,34,35,36,37);1H3,(H,3,4)/b26-13-;/t14-,1
InChI key	UGHHNQFYEVOFIV-VRDMTWHKSA-N
SMILES string	C[N+]1=CC=C(C=C1)C2=CSC(SC(CS[C@@]3([C@@H]4NC(/C(C5=NSC(NP(O)(O)=O)=N5)=N\OCC)=O)[H])=C(N3C4=O)C(O)=O)=N2.CC([O-])=O
assay	≥98% (HPLC)
form	powder
color	white to beige
solubility	DMSO: 2 mg/mL, clear (warmed)
storage temp.	−20°C
Quality Level	100

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