Miltenyi, 130-046-001, CD45RO MicroBeads, human

Name: CD45RO MicroBeads, human
Brand: Miltenyi
SKU: 130-046-001

Size:for 1×109 total cells

Catalog Number: 130-046-001

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Category

Human Primary Cells

TagsMACS Cell Separation Cell separation reagents MicroBeads and Isolation Kits T cells

Description

Background information
CD45RO is expressed on CD4+ and CD8+ T memory cells as well as on CD4+ effector T cells. CD45RO is also expressed on monocytes, macrophages, and granulocytes. The CD45RO antibody recognizes a 180 kDa isoform of the leukocyte common antigen (LCA).
CD45RO MicroBeads can be used for positive selection or depletion of CD45RO+ cells. For isolation of CD45RO+ T cell subsets, the CD45RO MicroBeads can be combined with CD4 and CD8 MACS® T Cell Isolation Kits1,2,7,8 or MultiSort Kits3,4. The CD45RO MicroBeads can also be used to isolate CD45RA+ cells from pre-sorted CD4+ or CD8+ T cells by depletion of CD45RO+ cells.5,7,8

Downstream applications
Cells isolated with CD45RO MicroBeads can be used for various studies, such as cytokine expression6 or receptor signaling.

Columns
For positive selection: MS, LS, XS, or autoMACS® Columns. For depletion: LD, D, or autoMACS Columns.

Overview
CD45RO MicroBeads were developed for positive selection or depletion of lymphocyte subsets from human PBMCs.

Ordering

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