Miltenyi, 130-046-401, CD22 MicroBeads, human

Name: CD22 MicroBeads, human
Brand: Miltenyi
SKU: 130-046-401

Size:for 1×109 total cells

Catalog Number: 130-046-401

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Category

Human Primary Cells

TagsMACS Cell Separation Cell separation reagents MicroBeads and Isolation Kits B cells

Description

Background information
In peripheral blood, cell surface expression of the CD22 antigen is found on mature B cells, but is lost during terminal differentiation to plasma cells. In bone marrow, surface expression of CD22 can be detected from the pre-B cell stage on. Cytoplasmic expression of CD22 can also be found in late pro-B cells and early pre-B cells.

Downstream applications
The purified B cells may be used for cell biological studies, such as analysis of signal transduction2, mixed lymphocyte responses1, antigen presentation, or for molecular studies, e.g. PCR analysis3.

Columns
For positive selection: MS, LS, XS, or autoMACS® Columns. For depletion: LD, D, or autoMACS Columns.

Overview
CD22 MicroBeads were developed for positive selection or depletion of human B cells from PBMCs, bone marrow, or single-cell suspensions from lymphoid tissues.

Ordering

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