Miltenyi, 130-090-663, Anti-DC (OX62) MicroBeads, rat

Name: Anti-DC (OX62) MicroBeads, rat
Brand: Miltenyi
SKU: 130-090-663

Size:for 1×109 total cells

Catalog Number: 130-090-663

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Category

Animal Primary Cells

TagsMACS Cell Separation Cell separation reagents MicroBeads and Isolation Kits Dendritic cells

Description

Background information
The monoclonal antibody OX62 recognizes the integrin αE2 subunit (molecular mass: 150 kDa). OX62 is expressed on the
CD4+ and the CD4- subset of dendritic cells but not on plasmacytoid dendritic cells in lymphoid tissue or on epidermal Langerhans cells. OX62 is also found on a subpopulation of epidermal TCRα/β+ or TCRγ/δ+ T cells and on a subset of folliculo-stellate-like (S100+) cells in the anterior pituitary. It is not expressed on macrophages.

Downstream applications
Isolated OX62+ dendritic cells were used, for example, for analysis of the differential phenotype, function, and migration of dendritic cell subsets.1

Columns
For positive selection: MS, LS, XS, or autoMACS® Columns. For depletion: LD, D, or autoMACS Columns.

Overview
Anti-DC (OX62) MicroBeads have been developed for the positive selection or depletion of OX62+ dendritic cells (DCs) from blood, lymphoid, and non-lymphoid tissue.

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