Miltenyi, 130-091-104, CD20 MicroBeads, human

Name: CD20 MicroBeads, human
Brand: Miltenyi
SKU: 130-091-104

Size:for 1×109 total cells

Catalog Number: 130-091-104

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Category

Human Primary Cells

TagsMACS Cell Separation Cell separation reagents MicroBeads and Isolation Kits B cells

Description

Background information
CD20 is a non-glycosylated transmembrane protein of 33–37 kDa that becomes heavily phosphorylated upon activation1,2. It is expressed exclusively on B cells, including pre-B cells, naive, mature, and activated B cells, B cell blasts, and the majority of malignant B cells, but not on early B cell progenitors or plasma cells2,3.

Downstream applications
Purified CD20+ B cells may be used in cell biological studies, such as analysis of signal transduction, chemotaxis, allergen response, apoptosis, or in molecular studies, e.g., subset-specific microarrays.

Columns
For positive selection: MS, LS, XS, or autoMACS® Columns. For depletion: LD, D, or autoMACS Columns.

Overview
CD20 MicroBeads were developed for positive selection or depletion of human CD20+ B cells from different cell sources such as human PBMCs, bone marrow, cell cultures or lymphoid tissues.

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