Miltenyi, 130-092-073, CD57 MicroBeads, human

Name: CD57 MicroBeads, human
Brand: Miltenyi
SKU: 130-092-073

Size:for 1×109 total cells

Catalog Number: 130-092-073

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Category

Human Primary Cells

TagsMACS Cell Separation Cell separation reagents MicroBeads and Isolation Kits NK cells

Description

Background information
The CD57 antigen, also known as HNK-1 or Leu-7, is an oligosaccharide antigenic moiety bound to surface proteins of certain cell types. CD57 is present on 15–20% of PBMCs, including subsets of NK cells and T cells and some neural cell types.1,2
CD57 has been shown to be expressed on late-stage CD8+ effector cells3 and terminally differentiated NK cells.
The frequency of CD57+ T lymphocytes is raised in a variety of diseases, for example, in rheumatoid arthritis4. Its expression is also increased on proliferation-incompentent or chronically activated CD8+ T cells in persistent viral infections, such as HIV.5

Columns
For positive selection: MS, LS, XS, or autoMACS® Columns. For depletion: LD, D, or autoMACS Columns.

Overview
CD57 MicroBeads were developed for the positive selection or depletion of CD57+ cells from human PBMCs, body fluids, or single-cell suspensions from tissue (e.g. lymphoid tissues).

Ordering

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