Miltenyi, 130-092-630, CD357 (GITR) Antibody, anti-mouse, pure

Name: CD357 (GITR) Antibody, anti-mouse, pure
Brand: Miltenyi
SKU: 130-092-630

Size:100 µg in 1 mL, CD4+ mouse splenocytes were stained with Anti-GITR-PE (A) or Anti-GITR-APC (B) and CD25-Biotin/Anti-Biotin-APC or CD25-PE. Cells were analyzed by flow cytometry. Cell debris and dead cells were excluded from the analysis based on scatter signals and propidium iodide fluorescence.

Catalog Number: 130-092-630

Pricing

Send an RFQ.

View RFQ List

Category

Biotin-Conjugated Secondary Antibodies

Pack Size100 µg

TagsMACS Antibodies Hybridomas

Description

Overview
Clone DTA-1 specifically recognizes mouse CD357, also known as glucocorticoid-induced TNF-receptor (GITR) or TNFRSF18, a member of the TNF receptor superfamily. It is expressed at low levels on resting T lymphocytes and at high levels on CD4+CD25+ regulatory T cells (Tregs). Activation of T cells upregulates GITR expression. Interaction of GITR with its ligand (GITRL) has been demonstrated to augment T cell activation, proliferation, cytokine production, as well as MAPKs and NF-κB activation. GITR plays an important role in the function of CD4+CD25+ Tregs.

Specifications

General

Clone	DTA-1
Clonality	monoclonal
Isotype	rat IgG2bκ
Isotype control	Isotype Control Antibody, rat IgG2b
Host	rat
Type of antibody	Primary antibodies
Species reactivity	mouse
Antigen	CD357 (GITR)
Molecular mass of antigen [kDa]	23
Entrez Gene ID	21936
RRID	AB_2922043, AB_871551, AB_2659972, AB_871552, AB_871550, AB_2659973

Ordering

Notice

Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
All quotations are subject to final confirmation, including product availability, lead time, batch information, shipping cost, and applicable export or handling requirements.
For quotation requests, please send an RFQ from website or contact:

[email protected]

Please send inquiries directly to us in the “To” field. Emails sent via BCC, mass mailing, or with unrelated recipients may be automatically filtered and will not be processed.