Miltenyi, 130-093-451, CD10 Antibody, anti-human, Biotin

Name: CD10 Antibody, anti-human, Biotin
Brand: Miltenyi
SKU: 130-093-451

Size:100 tests in 1 mL, Human white blood cells (WBCs) were stained with CD10 antibodies as well as with CD19 and CD45 antibodies and analyzed by flow cytometry using the MACSQuant® Analyzer. The Tandem Signal Enhancer has been used to increase binding specificity of tandem-dye–conjugated antibodies. CD45+ leukocytes were pre-gated for the analysis. Cell debris and dead cells were excluded from the analysis based on scatter signals and propidium iodide fluorescence or 4', 6-diamidino-2-phenylind

Catalog Number: 130-093-451

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Category

Mouse Isotype Controls

Pack Size100 tests

TagsMACS Antibodies Hybridomas

Description

Overview
Clone 97C5 recognizes the human CD10 antigen, the human common acute lymphoblastic leukemia antigen (CALLA). CD10 is a 100 kDa cell surface molecule identical to human membrane-associated neutral endopeptidase (NEP) and also known as neprilysin or enkephalinase. Human CD10 is expressed on a wide variety of normal and neoplastic cell types from different tissues including neural and hematopoietic cells. It is expressed on pre– and pro–B cells and is involved in B cell development and differentiation. The antigen is also present on mature neutrophils, T cell precursors, and some T cell leukemias/lymphomas. Furthermore, CD10 is expressed on neoplastic cells of several B lymphoid leukemias/lymphomas.

Specifications

General

Clone	97C5
Clonality	monoclonal
Isotype	mouse IgG1κ
Isotype control	Isotype Control Antibody, mouse IgG1
Host	mouse
Type of antibody	Primary antibodies
Species reactivity	human
Antigen	CD10
Molecular mass of antigen [kDa]	85
Distribution of antigen	B cells, epithelial cells, fibroblasts, granulocytes, ILC, stromal cells, T cells, leukemia cells, ES and iPS cells, bone marrow, brain, smooth muscle, gut, kidney
Entrez Gene ID	4311
RRID	AB_2857621, AB_2660860, AB_2660862, AB_2660863, AB_2660864, AB_2733329, AB_2733328, AB_2904674, AB_10831358, AB_2660858, AB_2660859, AB_2904673, AB_2819583, AB_2857649, AB_2660861, AB_2819598

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