Miltenyi, 130-093-452, CD10 MicroBead Kit, human

Background information
CD10, the human common acute lymphoblastic leukemia antigen (CALLA), is a 100 kDa cell surface molecule identical to human membrane-associated neutral endopeptidase (NEP) and also known as neprilysin or enkephalinase. Human CD10 is expressed on a wide variety of normal and neoplastic cell types from different tissues including neural and hematopoietic cells.
CD10 is expressed on pre– and pro–B cells and is involved in B cell development and differentiation. The antigen is also present on mature neutrophils, T cell precursors, some T cell leukemias/lymphomas and on neoplastic cells of several B cell leukemias/lymphomas.¹,²

Applications
The CD10 MicroBead Kit was developed for the enrichment or depletion of CD10+ cells from bone marrow or other cell sources. It can also be used for the isolation of CD10+ B cells from B cell leukemias/lymphomas.

Columns
For positive selection: MS, LS, XS, or autoMACS® Columns. For depletion: LD, D, or autoMACS Columns.

Overview
The CD10 MicroBead Kit was developed for the enrichment or depletion of CD10+ cells from bone marrow or other cell sources.