Miltenyi, 130-095-194, CD44 MicroBeads, human

Name: CD44 MicroBeads, human
Brand: Miltenyi
SKU: 130-095-194

Size:for 1×109 total cells

Catalog Number: 130-095-194

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Category

Mesenchymal Stem Cells

TagsMACS Cell Separation Cell separation reagents MicroBeads and Isolation Kits Cancer stem cells

Description

Background information
CD44 is a marker for many types of cancer stem cells (CSC), including breast CSCs that possess higher tumorigenicity and metastatic potential1, colorectal2, pancreatic3, and prostate4,5 CSCs. In addition, expression was observed in several cancers as well as on carcinoma cell lines. Here, it plays a role in cancer cell migration and matrix adhesion in response to a cellular microenvironment, thus enhancing cellular aggregation and tumor cell growth6. CD44 is also expressed on mesodermal cells, such as hematopoietic, fibroblastic, and glial cells.

Columns
For positive selection: LS, XS, or autoMACS® Columns. For depletion: LD, CS, D, or autoMACS Columns.
Note: This product is not suitable for cell separation with an MS Column.

Overview
CD44 MicroBeads have been specifically designed and optimized for the isolation or depletion of CD44+ cells from single-cell suspensions from solid tumors, including breast, pancreatic, colon, and prostate tissues or cancer cell lines.

Ordering

Notice

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