Miltenyi, 130-095-221, CD101 Antibody, anti-human, Biotin

Name: CD101 Antibody, anti-human, Biotin
Brand: Miltenyi
SKU: 130-095-221

Size:100 tests in 1 mL, Human peripheral blood mononuclear cells (PBMCs) were stained with CD101 antibodies as well as with CD4 antibodies and analyzed by flow cytometry using the MACSQuant® Analyzer. The Tandem Signal Enhancer has been used to increase binding specificity of tandem-dye–conjugated antibodies. Cell debris and dead cells were excluded from the analysis based on scatter signals and propidium iodide fluorescence or 4', 6-diamidino-2-phenylindole (DAPI) fluorescence, as in the case o

Catalog Number: 130-095-221

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Category

Mouse Isotype Controls

Pack Size100 tests

TagsMACS Antibodies Hybridomas

Description

Overview
Clone BB27 recognizes the CD101 antigen, also known as V7 or IGSF2, which is a 140 kDa type I transmembrane glycoprotein of the Ig gene superfamily. CD101 is expressed on monocytes, granulocytes, and subsets of dendritic cells (DCs). In addition, CD101 is expressed on certain subpopulations of T cells, in particular about 5–30% of FoxP3+ Treg cells in peripheral blood.
The interaction of CD101 with the antibody BB27 has been shown to inhibit T cell activation by allogeneic DCs or CD3 antibodies.

Specifications

General

Clone	BB27
Clonality	monoclonal
Isotype	mouse IgG1κ
Isotype control	Isotype Control Antibody, mouse IgG1
Host	mouse
Type of antibody	Primary antibodies
Species reactivity	human
Antigen	CD101
Molecular mass of antigen [kDa]	113
Distribution of antigen	dendritic cells, granulocytes, Langerhans cells, monocytes, red blood cells, T cells, lymphocytes, leukemia cells, thymocytes, lung, small intestine, spleen
Entrez Gene ID	9398
RRID	AB_10827694, AB_10829614, AB_2661058, AB_2661057, AB_2661055, AB_10828923, AB_2661056

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