Miltenyi, 130-097-859, Anti-PSA-NCAM MicroBead Kit, human and mouse

Name: Anti-PSA-NCAM MicroBead Kit, human and mouse
Brand: Miltenyi
SKU: 130-097-859

Size:for 1×109 total cells

Catalog Number: 130-097-859

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Category

Human Primary Cells

TagsMACS Cell Separation Cell separation reagents MicroBeads and Isolation Kits ES and iPS cells

Description

Background information
The Anti-PSA-NCAM antibody recognizes an epitope on polysialic acid (PSA) which, in vertebrates, is found linked to the extracellular domain of the neural cell adhesion molecule (NCAM, CD56).¹ PSA-NCAM, the highly polysialated form of NCAM, is predominantly expressed
in embryonic and neonatal neural tissue.² In vitro differentiation of human and mouse pluripotent stem cells under defined conditions revealed that neuronal progenitors, e.g. long-term self-renewing neuroepithelial-like stem cells, express the surface marker PSA-NCAM.³ Magnetically enriched, in vitro generated PSA-NCAM positive neural progenitors can be further differentiated into defined neuronal subtypes.

Columns
LS or autoMACS® Columns.

Overview
The Anti-PSA-NCAM MicroBead kit has been designed for the isolation of PSA-NCAM+ neural progenitors from differentiated ES or iPS cell cultures.

Ordering

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