Miltenyi, 130-101-966, CD81 Antibody, anti-mouse/rat, Biotin

Name: CD81 Antibody, anti-mouse/rat, Biotin
Brand: Miltenyi
SKU: 130-101-966

Size:30 µg in 1 mL, Immunofluorescence analysis of a mouse spleen cryosection fixed with ice-cold acetone. The section was stained using CD81 Antibody, anti-mouse/rat, PE (green) for 10 min at room temperature.

Catalog Number: 130-101-966

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Category

Biotin-Conjugated Secondary Antibodies

Pack Size30 µg

TagsMACS Antibodies Hybridomas

Description

Overview
CD81 is widely expressed and is involved in a variety of biological processes. In the brain it is expressed on astrocytes, oligodendrocytes, microglia, and endothelial cells. The CD81 antigen is a 26 kDa cell surface glycoprotein, also known as TAPA-1, and a member of the tetraspanin family, characterised by the presence of four hydrophobic domains. CD81 is known to complex with integrins, and mediates signal transduction events in the regulation of muscle cell fusion, myotube maintenance, signal transduction, cell development, activation, growth, and motility. The CD81 gene is localized in the tumor suppressor gene region and thus it is a candidate gene for malignancies.

Specifications

General

Clone	EAT2
Clonality	monoclonal
Isotype	hamster IgGκ
Host	hamster
Type of antibody	Primary antibodies
Species reactivity	mouse, rat, non-human primate
Cross-reactivity	rhesus monkey (Macaca mulatta), cynomolgus monkey (Macaca fascicularis)
Antigen	CD81
Molecular mass of antigen [kDa]	26
Distribution of antigen	B cells, endothelial cells, epithelial cells, granulocytes, monocytes, T cells, stem cells, leukocytes, lymphocytes, ES and iPS cells
Entrez Gene ID	12520
RRID	AB_2659292, AB_2889629, AB_2659291, AB_2659294, AB_2659295, AB_2659289, AB_2659290, AB_2659293

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