Miltenyi, 130-103-749, CD106 (VCAM-1) Antibody, anti-rat, PE

Name: CD106 (VCAM-1) Antibody, anti-rat, PE
Brand: Miltenyi
SKU: 130-103-749

Size:9 µg in 300 µL, Rat VCAM transfected cells were either stained with CD106 (VCAM-1) antibodies or corresponding isotype control antibodies (left peak) and analyzed by flow cytometry using the MACSQuant® Analyzer. Cell debris and dead cells were excluded from the analysis based on scatter signals and propidium iodide fluorescence.

Catalog Number: 130-103-749

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Category

Rat Isotype Controls

Pack Size9 µg

TagsMACS Antibodies Hybridomas

Description

Overview
Clone MR106 recognizes the CD106 antigen, a 110 kDa transmembrane protein also known as vascular cell adhesion protein 1 (VCAM-1). CD106 is expressed on bone marrow stromal cells, myeloid cells, and dendritic cells, but not on peripheral leukocytes. Expression on endothelial cells is upregulated upon inflammatory cytokine stimulation. CD106 is an endothelial ligand for the very late antigen-4 (VLA-4 or α4β1) of the β1 subfamily of integrins, and for integrin α4β7. It mediates the adhesion of lymphocytes, monocytes, eosinophils, and basophils to vascular endothelium. CD106 also functions in leukocyte-endothelial cell signal transduction, and it may play a role in the development of atherosclerosis and rheumatoid arthritis.

Specifications

General

Clone	MR106
Clonality	monoclonal
Isotype	mouse IgG1κ
Isotype control	Isotype Control Antibody, mouse IgG1
Host	mouse
Type of antibody	Primary antibodies
Species reactivity	rat
Antigen	CD106 (VCAM-1)
Molecular mass of antigen [kDa]	79
Distribution of antigen	endothelial cells, macrophages, dendritic cells, myeloid cells, stromal cells
Entrez Gene ID	25361
RRID	AB_2654460, AB_2654459, AB_2654462, AB_2654461

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