Miltenyi, 130-104-169, StemMACS™ Y27632

Name: StemMACS™ Y27632
Brand: Miltenyi
SKU: 130-104-169

Size:5× 2 mg

Catalog Number: 130-104-169

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Category

Small Molecule Inhibitors for Stem Cells

TagsMACS Cell Culture and Stimulation Small Molecules

Description

Background information
Rho-associated kinase is found in two isoforms, ROCK I (p160ROCK, ROCKβ) and ROCK II (ROCKα), both of which are inhibited by Y27632. The inhibition is reversible and competitive with respect to ATP.

Applications
Published applications for Y27632 include:
- Improved survival of human pluripotent stem cells after dissociation into single cells, e.g. during cell passaging or cell separation1
- Improved survival after thawing2

Overview
StemMACS™ Y27632 is a selective small molecule inhibitor of Rho-associated kinase (ROCK).

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