Miltenyi, 130-104-170, StemMACS™ PD0325901

Name: StemMACS™ PD0325901
Brand: Miltenyi
SKU: 130-104-170

Size:5× 2 mg

Catalog Number: 130-104-170

Pricing

Send an RFQ.

View RFQ List

Category

Small Molecule Inhibitors for Stem Cells

TagsMACS Cell Culture and Stimulation Small Molecules

Description

Background information
PD0325901 is a derivative of the MEK inhibitor CI-1040 and shows improved cell permeability and higher potency towards ERK1/2 (IC50=0.33 nM). In pluripotent stem cell research, inhibition of the MAPK signaling pathway with PD0325901 has been used to enhance reprogramming and sustain pluripotent stem cell selfrenewal.

Applications
Published applications for PD0325901 include:
- Naïve, ground state culture of murine ES and iPS cells (Ying et al.)
- Improved reprogramming efficiency when combined with SB431542 and Thiazovivin (Lin et al.)

Overview
StemMACS™ PD0325901 is a selective small molecule inhibitor of MEK (mitogen-activated protein kinase, MAPK/ERK kinase), a key component of the Ras/Raf/MEK/ERK signaling pathway.

Ordering

Notice

Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
All quotations are subject to final confirmation, including product availability, lead time, batch information, shipping cost, and applicable export or handling requirements.
For quotation requests, please send an RFQ from website or contact:

[email protected]

Please send inquiries directly to us in the “To” field. Emails sent via BCC, mass mailing, or with unrelated recipients may be automatically filtered and will not be processed.