Miltenyi, 130-104-464, StemMACS™ RG108

Name: StemMACS™ RG108
Brand: Miltenyi
SKU: 130-104-464

Size:10 mg

Catalog Number: 130-104-464

Pricing

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Category

Small Molecule Inhibitors for Stem Cells

Pack Size10 mg

TagsMACS Cell Culture and Stimulation Small Molecules

Description

Background information
StemMACS™ RG108 is a cell permeable and selective inhibitor of DNA methyltransferase (DNMT). RG108 is a non-nucleoside inhibitor that binds non-covalently and reversible to the active center (IC50 = 115 nM). It has been used as an epigenetic modifier that induces DNA demethylation and reactivation of silenced tumor suppressor genes. In pluripotent stem cell research, RG108 can enhance reprogramming efficiency.

Applications
Published applications for RG108 include:
- Inhibition of DNA Methyltransferase1
- Increase of reprogramming efficiency2

Overview
StemMACS™ RG108 is a selective small molecule inhibitor of DNA methyltransferase (DNMT).

Ordering

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