Miltenyi, 130-105-221, CD115 Antibody, anti-mouse, Vio® Bright FITC

Name: CD115 Antibody, anti-mouse, Vio® Bright FITC
Brand: Miltenyi
SKU: 130-105-221

Size:9 µg in 300 µL, Mouse bone marrow cells were stained with Anti-CD115 antibodies as well as with Anti-Ly-6C antibodies and analyzed by flow cytometry using the MACSQuant® Analyzer. Cell debris and dead cells were excluded from the analysis based on scatter signals and propidium iodide fluorescence.

Catalog Number: 130-105-221

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Category

Rat Isotype Controls

Pack Size9 µg

TagsMACS Antibodies Hybridomas

Description

Overview
Clone AFS98 recognizes the protein tyrosine kinase transmembrane receptor for macrophage colony-stimulating factor (M-CSF), also known as CSF-1 and interleukin 34 (IL-34). CD115 is a single-pass type I membrane protein. Receptor activation induces homo-dimerization, which leads to phosphorylation and ubiquitinylation of intracellular residues. CD115 is expressed on mouse monocytes, macrophages, and osteoclasts, as well as on common dendritic cell precursors and macrophage/dendritic cell precursors.

Specifications

General

Clone	AFS98
Clonality	monoclonal
Isotype	rat IgG2aκ
Isotype control	Isotype Control Antibody, rat IgG2a
Host	rat
Type of antibody	Primary antibodies
Species reactivity	mouse
Antigen	CD115
Molecular mass of antigen [kDa]	107
Distribution of antigen	dendritic cells, macrophages, osteoclasts, myeloid leukemia cells, breast, smooth muscle
Entrez Gene ID	12978
RRID	AB_2819410, AB_2660278, AB_2660281, AB_2660280, AB_2660279, AB_2660273, AB_2660272

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