Miltenyi, 130-105-375, CD205 (DEC205) Antibody, anti-mouse, PE-Vio® 770

Name: CD205 (DEC205) Antibody, anti-mouse, PE-Vio® 770
Brand: Miltenyi
SKU: 130-105-375

Size:30 µg in 1 mL, Mouse spleen cells were stained with CD8-conjugated antibodies as well as with CD205 (DEC205) antibodies conjugated to PE (A), APC (B), or Biotin (C). Cells stained with CD205 (DEC205)-Biotin were stained with Anti-Biotin-PE in addition. Samples were then analyzed by flow cytometry. Cell debris and dead cells were excluded from the analysis based on scatter signals and PI fluorescence.

Catalog Number: 130-105-375

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Category

Biotin-Conjugated Secondary Antibodies

Pack Size30 µg

TagsMACS Antibodies Hybridomas

Description

Overview
The CD205 antibody recognizes a 205 kDa integral membrane glycoprotein also known as DEC205 (dendritic and epithelial cells, 205 kDa).1,2 This membrane protein acts as an endocytic receptor and thereby mediates efficient processing and presentation of antigens in vivo, leading to the induction of T cell immunity or tolerance3. CD205 is expressed at high levels on mouse dendritic cells (DCs) in the skin (Langerhans cells), on DCs residing in the T cell areas of peripheral lymphoid organs, and on DCs generated in vitro from bone marrow progenitors.4 To a much lower extent, CD205 is also expressed on mature B cells, granulocytes, and T cells.1,2

Specifications

General

Clone	NLDC-145
Clonality	monoclonal
Isotype	rat IgG2aκ
Isotype control	Isotype Control Antibody, rat IgG2a
Host	rat
Type of antibody	Primary antibodies
Species reactivity	mouse
Antigen	CD205 (DEC205)
Molecular mass of antigen [kDa]	195
Distribution of antigen	dendritic cells, epithelial cells, Langerhans cells, thymocytes, spleen
Entrez Gene ID	17076
RRID	AB_2660241, AB_2660238, AB_2660239, AB_2660240, AB_2660236, AB_2660237

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